What is rhabdomyolysis?

Rhabdomyolysis is characterized by the breakdown of muscle tissue, resulting in the release of intracellular components, particularly myoglobin and potassium, into the bloodstream. This condition can occur due to various factors, such as trauma, extreme physical exertion, certain medications, or prolonged immobility. The release of myoglobin can lead to kidney damage as it is filtered through the renal system, potentially causing acute kidney injury. Additionally, elevated potassium levels from damaged muscle cells can lead to cardiac complications, making it critical to recognize and address this condition promptly in emergency and clinical settings.

Understanding rhabdomyolysis is essential for healthcare providers, especially in trauma and emergency care, due to its serious implications, including the potential for renal failure and electrolyte imbalances.